BDBM50371704 CHEMBL270415

SMILES Nc1c2C(=O)c3ccccc3C(=O)c2c(Br)cc1S([O-])(=O)=O

InChI Key InChIKey=QZZSAWGVHXXMID-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371704   

TargetP2Y purinoceptor 2(Mus musculus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50371704(CHEMBL270415)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50371704(CHEMBL270415)
Affinity DataIC50:  6.80E+4nMAssay Description:Displacement of ssDNA with ATTGTCA (m6A) CAGCAGA-FAM from human FTO measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50371704(CHEMBL270415)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed