BDBM50373886 3-Deazathiamine::CHEMBL401772

SMILES Cc1c(Cc2cnc(C)nc2N)csc1CCO

InChI Key InChIKey=HLBXMICRXICHJQ-UHFFFAOYSA-N

Data  1 IC50  3 Kd  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50373886   

TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50373886(3-Deazathiamine | CHEMBL401772)
Affinity DataKd:  12nMAssay Description:Inhibition of apo-transketolase by coupled TPPK/Apo-TK enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50373886(3-Deazathiamine | CHEMBL401772)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50373886(3-Deazathiamine | CHEMBL401772)
Affinity DataKd:  1.80E+4nMAssay Description:Inhibition of apo-transketolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed