BDBM50375590 CHEMBL1552

SMILES C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=GHCZAUBVMUEKKP-GYPHWSFCSA-N

Data  1 KI  2 EC50

PDB links: 15 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375590   

TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataKi:  7.00E+3nMAssay Description:TP_TRANSPORTER: competitive inhibition of Taurocholate uptake in membrane vesicles prepared from High Five cells infected with the ABCB11 baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataEC50:  3.00E+3nMAssay Description:Binding affinity for Farnesoid X Receptor (FXR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataEC50:  3.88E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed