BDBM50375708 CHEMBL403251

SMILES CCc1cc(Cl)ccc1Oc1cc(C)ncc1CNC

InChI Key InChIKey=JEYCKWDBZTXTRQ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50375708   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]Citalopram uptake in human 5HTT transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataKi:  74nMAssay Description:Inhibition of [3H]Nisoxetine uptake in human noradrenaline transporter transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataKi:  4.35E+3nMAssay Description:Inhibition of [3H]WIN-35428 uptake in human DAT transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed