BDBM50375715 CHEMBL256293

SMILES CCc1cc(Cl)ccc1Oc1cc(C)ncc1CN(C)C

InChI Key InChIKey=TWSKMFBDRRENNV-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375715   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]Citalopram uptake in human 5HTT transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]Nisoxetine uptake in human noradrenaline transporter transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed