BDBM50375816 CHEMBL407622

SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N

InChI Key InChIKey=FYYJYCODYXFNFD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375816   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375816(CHEMBL407622)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375816(CHEMBL407622)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375816(CHEMBL407622)
Affinity DataIC50:  8.10nMAssay Description:Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed