BDBM50377759 CHEMBL255497

SMILES Clc1ccc(CS(=O)(=O)Nc2cccc(c2)-c2[nH]c(nc2-c2ccnc(NCCN3CCNC3=O)n2)C2CC2)cc1Cl

InChI Key InChIKey=NTUPINFPCXIWMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377759   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377759(CHEMBL255497)
Affinity DataIC50:  41nMAssay Description:Inhibition of C-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377759(CHEMBL255497)
Affinity DataIC50:  343nMAssay Description:Inhibition of B-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed