BDBM50377761 CHEMBL430413
SMILES CNc1nccc(n1)-c1nc([nH]c1-c1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1)C1CC1
InChI Key InChIKey=ZIRQSEOPGSAMHR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50377761
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of C-RAF kinaseMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of B-RAF kinaseMore data for this Ligand-Target Pair