BDBM50377762 CHEMBL256775

SMILES NC(=O)c1cccc(Nc2nccc(n2)-c2nc([nH]c2-c2cccc(NC(=O)Cc3ccc(Cl)cc3)c2)C(F)(F)F)c1

InChI Key InChIKey=ZDWXGFSUCOUHQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377762   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377762(CHEMBL256775)
Affinity DataIC50:  108nMAssay Description:Inhibition of B-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377762(CHEMBL256775)
Affinity DataIC50:  17nMAssay Description:Inhibition of C-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed