BDBM50377763 CHEMBL258454

SMILES CNc1nccc(n1)-c1nc([nH]c1-c1cccc(NC(=O)Cc2ccc(Cl)cc2)c1)C(F)(F)F

InChI Key InChIKey=YVQXWWGTOPSSIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377763   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377763(CHEMBL258454)
Affinity DataIC50:  30nMAssay Description:Inhibition of B-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377763(CHEMBL258454)
Affinity DataIC50:  2nMAssay Description:Inhibition of C-RAF kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed