BDBM50378014 CHEMBL1627308::US8748608, 35
SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3[nH]2)CC1
InChI Key InChIKey=HUNDNZUNCNQCRK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50378014
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.37nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.40nMAssay Description:Displacement of [125]IABN from human D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 132nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.92E+3nMAssay Description:Displacement of [125]IABN from human D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataIC50: 12.1nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair