BDBM50378780 (S)-VOROZOLE

SMILES Cn1nnc2ccc(cc12)[C@H](c1ccc(Cl)cc1)n1cncn1

InChI Key InChIKey=XLMPPFTZALNBFS-INIZCTEOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50378780   

TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50:  29nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50:  9.50E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50:  1.38nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed