BDBM50379081 Aigialomycin D::CHEMBL1173442

SMILES CC1C\C=C\C(O)C(O)CC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI Key InChIKey=NHAQNKDEUQPSIX-JHMJBTLWSA-N

Data  5 IC50  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50379081   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CDK2/cyclin A using 5-FAM-GGGPATPKKAKKL-COOH as substrate after 1 hr by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataIC50:  450nMAssay Description:Inhibition of MNK2 using 5-FAM-TATKSGSTTKNRFVV-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataKd:  1.20E+4nMAssay Description:Inhibition of PRKCEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataKd:  160nMAssay Description:Inhibition of MNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataKd:  300nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataKd:  1.00E+3nMAssay Description:Inhibition of AXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379081(Aigialomycin D | CHEMBL1173442)
Affinity DataKd:  260nMAssay Description:Inhibition of PLK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed