BDBM50379898 CHEMBL2011983
SMILES CN1C(N)=N[C@](C1=O)(c1ccccc1)c1cccc(c1)-c1cccnc1
InChI Key InChIKey=PNSQCPQDRVOKMA-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50379898
Affinity DataKi: 110nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP swedish and london mutant assessed as decrease of amyloid-beta40 level after 4 hrs by electrochemi...More data for this Ligand-Target Pair