BDBM50380664 CHEMBL2017287

SMILES COc1cc2c3n(C(C)c4ccccc4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C

InChI Key InChIKey=JNYUGWPUYNNZOZ-UHFFFAOYSA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50380664   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50380664(CHEMBL2017287)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50380664(CHEMBL2017287)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50380664(CHEMBL2017287)
Affinity DataKd:  37nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated tetra-acetylated Histone H4 peptide as substrate and measured for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))TBA
LigandPNGBDBM50380664(CHEMBL2017287)
Affinity DataKd:  32nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) using biotinylated tetra-acetylated Histone H4 peptide as substrate and measured for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50380664(CHEMBL2017287)
Affinity DataKd:  39nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotinylated tetra-acetylated Histone H4 peptide as substrate and measured for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed