BDBM50380981 CHEMBL2017109
SMILES CC(=O)NCCc1ccccc1-c1onc([C@H]2CNCC[C@@H]2c2ccc(F)c(F)c2)c1Br
InChI Key InChIKey=YYTAVUDZQYYPJI-MJGOQNOKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50380981
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 1.95E+4nMAssay Description:Binding affinity to human ErgMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Reversible inhibition of CYP3A4-mediated conversion of testosterone to 6-beta-hydroxy-testosterone after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate after 3 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate pretreated for 10 mins measured after 3 hrs ...More data for this Ligand-Target Pair