BDBM50381161 CHEMBL2018219

SMILES Cc1nn2c(nc(cc2=O)N2CCOCC2)n1Cc1cccc(c1C)C(F)(F)F

InChI Key InChIKey=ZUZPKPRXZFEGST-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50381161   

LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  630nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  790nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed