BDBM50381477 CHEMBL2017410

SMILES COc1cc(ccc1-n1cnc(C)c1)-c1cn(CC(=O)Nc2cccc3ccccc23)nn1

InChI Key InChIKey=MYWAKYXOZTWEIR-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50381477   

TargetProbable G-protein coupled receptor 142(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50381477(CHEMBL2017410)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50381477(CHEMBL2017410)
Affinity DataEC50:  115nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381477(CHEMBL2017410)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50381477(CHEMBL2017410)
Affinity DataEC50:  37nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50381477(CHEMBL2017410)
Affinity DataEC50:  252nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed