BDBM50381485 CHEMBL2017593
SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(O)(CC1)C1CC1
InChI Key InChIKey=LJPAFJGPXZHKBA-NYYWCZLTSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50381485
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories
Curated by ChEMBL
Dr. Reddy'S Laboratories
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Dr. Reddy'S Laboratories
Curated by ChEMBL
Dr. Reddy'S Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories
Curated by ChEMBL
Dr. Reddy'S Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair