BDBM50382406 CHEMBL1606364

SMILES Fc1ccc(cc1)S(=O)(=O)N1CCN(CC(=O)Nc2ccccc2F)CC1

InChI Key InChIKey=FDPMJYWRCOLAOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50382406   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50382406(CHEMBL1606364)
Affinity DataIC50:  9.30E+3nMAssay Description:Negative allosteric modulation of human nAChR alpha4beta2 expressed in HEK ts201 cells assessed as inhibition of epibatidine-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382406(CHEMBL1606364)
Affinity DataIC50:  1.96E+4nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium accu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50382406(CHEMBL1606364)
Affinity DataIC50:  9.80E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium accu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed