BDBM50383684 CHEMBL1961795
SMILES CC(C)(C)OC(=O)CN(Cc1ccc(s1)[N+]([O-])=O)Cc1ccc(Cl)cc1
InChI Key InChIKey=WYSLOKHVFKLWOU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50383684
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to LXRalpha (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Agonist activity at biotinylated REV-ERBalpha (unknown origin) assessed as increase in biotinylated NCOR peptide recruitment after 1 hr by FRET assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Agonist activity at Rev-Erb alpha (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at Rev-erbalpha assessed as NCoR recruitment by FRET assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Agonist activity at Rev-Erbalpha expressed in HEK293 cells coexpressing BamII promoter assessed as repression of transcription after 24 hrs by dual-G...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Agonist activity at Rev-erbalpha assessed as repression of transcription by luciferase-reporter gene assayMore data for this Ligand-Target Pair