BDBM50383861 CHEMBL2031160

SMILES OC(=O)[C@H](Cc1ccc(OCCc2ccc3CCCNc3n2)cc1)NC(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=XUISHROIRBHOIM-QFIPXVFZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383861   

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383861(CHEMBL2031160)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at integrin alpha5beta1 in human K562 cells assessed as inhibition of cell adhesion in presence of 630 uM human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383861(CHEMBL2031160)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383861(CHEMBL2031160)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383861(CHEMBL2031160)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of integrin alpha2b beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed