BDBM50383883 CHEMBL2029369

SMILES COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1[C@@]1(C[C@H]2CC[C@H]1C2)c1ccccc1

InChI Key InChIKey=HTVMFNNDIAJZQI-DDIQADRFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383883   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383883(CHEMBL2029369)
Affinity DataIC50:  460nMAssay Description:Inhibition of 5-lipoxygenase-activating protein in human polymorphonuclear cells assessed as inhibition of calcium ionophore-induced LTB4 production ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383883(CHEMBL2029369)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]L-691,831 from 5-lipoxygenase-activating protein in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed