BDBM50384715 CHEMBL2037201

SMILES Clc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)N3CCCNCC3)c2c1

InChI Key InChIKey=IRPPYJZDFMMBBV-RCCKNPSSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384715   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Pim3 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)
Affinity DataIC50:  150nMAssay Description:Inhibition of Flt3 using EAIYAAPFAKKK as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384715(CHEMBL2037201)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed