BDBM50386738 CHEMBL1834565

SMILES COc1cccc(OC)c1\C=C\C(=O)c1cn(C)c2ccccc12

InChI Key InChIKey=JXVXOLFHHDFJGZ-VAWYXSNFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386738   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Bmssi Umr 5086 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50386738(CHEMBL1834565)
Affinity DataIC50:  270nMAssay Description:Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells after 48 hrs by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed