BDBM50387134 4-ureidophenyl sulfamate ring derivative 3s::CHEMBL2047814

SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2c(F)cc(F)cc2Br)cc1

InChI Key InChIKey=JQNKTKMEJUJUJM-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50387134   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  5nMAssay Description:Inhibition of human carbonic anhydrase-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  6nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universit£

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  84nMAssay Description:Inhibition of recombinant full length Candida albicans NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  641nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  682nMAssay Description:Inhibition of human carbonic anhydrase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of human carbonic anhydrase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387134(4-ureidophenyl sulfamate ring derivative 3s | CHEM...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed