BDBM50387189 CHEMBL2048204
SMILES COc1ccc(cc1CSc1nc2cc(F)ccc2n1CC(O)=O)C(=O)N1CCc2ccccc12
InChI Key InChIKey=WYTXJLWGOIYXTG-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50387189
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4 using testosterone as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]-PGD2 from human CRTh2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by flow...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-PGD2 from human CRTh2 receptor expressed in HEK293 cells in presence of 0.5% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK293 cells assessed as inhibition of PGD2-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-PGD2 from human DP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair