BDBM50388183 CHEMBL2057915
SMILES CN1CCN(C)C(=O)[C@H]1c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(NC(=O)c3cc4CCCCc4s3)c2C)cc1
InChI Key InChIKey=CDOOFZZILLRUQH-GDLZYMKVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50388183
Affinity DataEC50: 380nMAssay Description:Inhibition of BTK in human whole blood B-cells assessed as inhibition of both anti-IgD-stimulated CD69 expressionMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Inhibition of BTK in human whole blood basophils assessed as inhibition of both anti-IgE-stimulated CD63 expressionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair