BDBM50389154 CHEMBL2064666
SMILES COc1c(Nc2ncc(Cl)c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(N)=O)n2)ccc2CC[C@@H](CCc12)N1CCOCC1
InChI Key InChIKey=LAJAFFLJAJMYLK-CVOKMOJFSA-N
Data 29 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50389154
Affinity DataIC50: 88nMAssay Description:Inhibition of human Flt3More data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of human FesMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of human FerMore data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human CHK2More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human BRKMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human ARK5More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human ACK1More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of ALK tyrosine phosphorylation in human Karpas-299 cells after 2 hrs in presence of mouse plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human ALK cytoplasmic domain expressed in baculovirus using GST-PLCgamma as substrate preincubated for 15 mins before substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human Rsk4More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human Rsk3More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human Rsk2More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human Rsk1More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of human JNK1alpha1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Cephalon
Curated by ChEMBL
Cephalon
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human GCKMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human Flt4More data for this Ligand-Target Pair