BDBM50389286 CHEMBL2063761

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2CS(=O)(=O)Cc2c(n1)N1C[C@@H]2C[C@H]1CO2

InChI Key InChIKey=JPOAQDAFYRTLEO-GJZGRUSLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389286   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389286(CHEMBL2063761)
Affinity DataKi:  62nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389286(CHEMBL2063761)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed