BDBM50390707 CHEMBL2070316::US8486964, 1
SMILES Fc1ccc(cc1)C1(CC1)C(=O)N1CC2CC2(C1)c1c[nH]c2ncccc12
InChI Key InChIKey=NVEWYSISVYQERO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50390707
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:Inhibition of 11-beta-HSD-1 enzyme assay using human recombinant 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) enzyme was expressed in ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMpH: 7.4 T: 2°CAssay Description:Inhibition of 11-beta-HSD-1 enzyme assay using human recombinant 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) enzyme was expressed in ...More data for this Ligand-Target Pair
Affinity DataIC50: 670nMpH: 7.4 T: 2°CAssay Description:Inhibition of 11-beta-HSD-1 enzyme assay using human recombinant 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) enzyme was expressed in ...More data for this Ligand-Target Pair