BDBM50391088 CHEMBL2087360

SMILES Fc1ccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)cc1Cl

InChI Key InChIKey=DHDUWXQFEYJFTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391088   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang Betapharma

Curated by ChEMBL
LigandPNGBDBM50391088(CHEMBL2087360)
Affinity DataIC50:  45nMAssay Description:Inhibition of EGFR-mediated intracellular tyrosine phosphorylation in EGF-stimulated human A431 cells after 2.5 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang Betapharma

Curated by ChEMBL
LigandPNGBDBM50391088(CHEMBL2087360)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFR using GST-Crk as substrate assessed as phosphorylated Crk level after 20 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed