BDBM50391762 CHEMBL2146870
SMILES O=C1OCc2cc(CCN3CCN(CCc4ccc5C(=O)OCc5c4)CC3)ccc12
InChI Key InChIKey=PYUXNNYRCHVGKZ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50391762
Affinity DataIC50: 26nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [35S]MK-499 from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [35S]MK-499 from human ERGMore data for this Ligand-Target Pair