BDBM50391772 CHEMBL2146851

SMILES N#Cc1ccc(CCN2CCN(CCc3ccc4nonc4c3)CC2)cc1

InChI Key InChIKey=GEWMFRYQVAYXIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391772   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391772(CHEMBL2146851)
Affinity DataIC50:  42nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391772(CHEMBL2146851)
Affinity DataIC50:  42nMAssay Description:Inhibition of hERG (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391772(CHEMBL2146851)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed