BDBM503925 US11034692, Compound 205::trans-N-(8-amino-5-methyl-6-(4- methylpyridin-3-yl)-2,7-naphthyridin-3- yl)-2- (cyanomethyl)cyclopropanecarboxamide

SMILES Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1C

InChI Key InChIKey=VOYOLLACSNQFJX-ZFWWWQNUSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503925   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM503925(US11034692, Compound 205 | trans-N-(8-amino-5-meth...)
Affinity DataKi:  0.0880nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent