BDBM50392655 CHEMBL2153710

SMILES CN(CC1CCc2nc(N)nc(N)c2N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=JMOWMSBWWOKCKJ-BPARTEKVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392655   

TargetMethionine synthase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50392655(CHEMBL2153710)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of methionine synthase in human HL60 cells using L-homocysteine as substrate incubated for 3 hrs prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50392655(CHEMBL2153710)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human recombinant DHFR using dihydrofolate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed