BDBM50392995 CHEMBL2152523

SMILES C1CCN(CC1)[C@@H]([C@H](N1CCCCC1)c1ccccc1)c1ccccc1

InChI Key InChIKey=MTYFDEYZRYWPAI-DNQXCXABSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50392995   

TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in CHO cells by high throughput planar patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Kv1.5 ion channel after 3 mins by high-throughput planar patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human Kv1.5 expressed in CHO cells by IonWork high-throughput electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  126nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  130nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392995(CHEMBL2152523)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed