BDBM50393034 CHEMBL2152704

SMILES Cc1ccc(O)cc1-n1c2ncnc(N)c2c2CCCCc2c1=O

InChI Key InChIKey=ZQQZSFIPDUAFMC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50393034   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  300nMAssay Description:Inhibition of EphB4 by FRET assay in presence of 30 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  160nMAssay Description:Inhibition of EphB4 in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  338nMAssay Description:Inhibition of recombinant Src catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  930nMAssay Description:Inhibition of human full length EphB4 expressed in MEF cells assessed as inhibition of human ephrin B2/FC chimera-stimulated receptor autophosphoryla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of recombinant Lck catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of recombinant EGFR catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50:  864nMAssay Description:Inhibition of recombinant Abl1 catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed