BDBM50393090 CHEMBL2152905

SMILES CCn1cc(cc(C(F)F)c1=O)[C@@]1(N=C(N)c2c1cccc2F)c1cccc(c1)-c1cncc(c1)C#CC

InChI Key InChIKey=GZUAKTAFZQGCMX-PMERELPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393090   

TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393090(CHEMBL2152905)
Affinity DataIC50:  6nMAssay Description:Inhibition of BACE1 by diluted TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393090(CHEMBL2152905)
Affinity DataIC50:  4nMAssay Description:Inhibition of BACE1 by secreted AAPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed