BDBM50393095 CHEMBL2152910::US9346827, 14
SMILES NC1=N[C@@]2(COCC1)c1cc(ccc1Oc1cnc(cc21)-c1ccnc(F)c1)-c1cccnc1F
InChI Key InChIKey=ZASOWXQELAKJDI-SANMLTNESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50393095
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair