BDBM50393440 CHEMBL2159498

SMILES CC(=O)c1cc(c(Sc2ccc(F)cc2F)s1)[N+]([O-])=O

InChI Key InChIKey=RMAMGGNACJHXHO-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50393440   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataEC50:  8.00E+3nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataEC50:  8.70E+3nMAssay Description:Inhibition of USP47 by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of USP7 (unknown origin) by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human recombinant USP47 expressed in Escherichia coli sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of full-length recombinant USP7 (unknown origin) expressed in Sf9 cells using Ub-EKL as substrate preincubated for 30 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant USP7 expressed in Escherichia coli sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of USP7 (unknown origin) by Ub-PLA2 assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393440(CHEMBL2159498)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition and subsequent incubation in da...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed