BDBM50393771 CHEMBL2159332

SMILES OC(=O)CCNC(=O)c1ccc(Cn2nc(cc2-c2ccc3ccc(OC(F)(F)F)cc3c2)-c2cc(Cl)cc(Cl)c2)cc1

InChI Key InChIKey=QZFBRKKWYQRTKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393771   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393771(CHEMBL2159332)
Affinity DataIC50:  64nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393771(CHEMBL2159332)
Affinity DataIC50:  189nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed