BDBM50394373 CHEMBL2159777

SMILES O=C(N1CCN(Cc2cccc(c2)-c2ccccc2)CC1)n1nnc2ccccc12

InChI Key InChIKey=UGSNUFMXTDVKNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394373   

TargetMonoglyceride lipase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50394373(CHEMBL2159777)
Affinity DataIC50:  23nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50394373(CHEMBL2159777)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed