BDBM50395003 CHEMBL2163476::US9708370, DBG-188p

SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O

InChI Key InChIKey=BCSZFYFJCSDJSC-BBMDXEPMSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395003   

TargetPlatelet glycoprotein 4(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50395003(CHEMBL2163476 | US9708370, DBG-188p)
Affinity DataIC50:  9.61E+3nMAssay Description:Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor [D538G](Homo sapiens (Human))
Valorisation-Recherche, Limited Partnership

US Patent
LigandPNGBDBM50395003(CHEMBL2163476 | US9708370, DBG-188p)
Affinity DataEC50:  808nMAssay Description:GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet glycoprotein 4(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50395003(CHEMBL2163476 | US9708370, DBG-188p)
Affinity DataIC50:  9.61E+3nMpH: 7.3Assay Description:Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395003(CHEMBL2163476 | US9708370, DBG-188p)
Affinity DataIC50:  808nMAssay Description:Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed