BDBM50395230 CHEMBL2164671

SMILES CN(C)C(=O)[C@@H]1CCCC[C@H]1C(=O)NCC#N

InChI Key InChIKey=COAAWIOBUIHLMS-NXEZZACHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395230   

TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395230(CHEMBL2164671)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human recombinant CatS assessed as suppression of enzyme-mediated Z-Val-Val-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395230(CHEMBL2164671)
Affinity DataIC50:  9.82E+3nMAssay Description:Inhibition of human recombinant CatB assessed as suppression of enzyme-mediated Z-Arg-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395230(CHEMBL2164671)
Affinity DataIC50:  257nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395230(CHEMBL2164671)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant CatL assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed