BDBM50395573 CHEMBL2165115::UNC10108006::US9156822, 24
SMILES Clc1cccc(C2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl
InChI Key InChIKey=JEZQFKLGYQTDDK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50395573
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 10.9nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 11nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 20nMAssay Description:Agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataEC50: 25nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair