BDBM50395609 CHEMBL2165320
SMILES O=C1CCc2cc(c(OCc3ccccc3)cc2N1)-c1cccnc1
InChI Key InChIKey=VGFAZLJERHRJJT-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50395609
Affinity DataIC50: 44nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 25 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 45 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human CYP19 expressed in hamster fibroblast using 500 nM [1beta-3H] androstenedione as substrate by HPLC analysisMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human CYP11B1 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging methodMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human CYP11B2 expressed in V79MZh cells using [14C]-11-deoxycorticosterone as substrate by HPTLC/phosphoimaging methodMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of CYP19 in human placental microsomes using [1beta-3H]-androstendione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysisMore data for this Ligand-Target Pair