BDBM50395709 CHEMBL2164087

SMILES Cc1nc(CNc2nc(NCCC=C)nc(n2)N2CCC[C@@H]2CNS(=O)(=O)c2ccc(cc2)C(F)(F)F)cs1

InChI Key InChIKey=HHJXHPGHWQBYAU-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395709   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50395709(CHEMBL2164087)
Affinity DataIC50:  430nMAssay Description:Inhibition of human ADAMTS-5 expressed in CHO cells using WAAG-3R as substrate preincubated for 15 mins measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed