BDBM50396016 CHEMBL2169918

SMILES N[C@@H](CCCN(CCI)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccccc3)ncnc12)C(O)=O

InChI Key InChIKey=GLCOSOCNOCATCH-GMDRLUGNSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50396016   

TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396016(CHEMBL2169918)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CARM1 expressed in Escherichia coli BL21 (DE3) using [3H]-SAM as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396016(CHEMBL2169918)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SUV39H1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396016(CHEMBL2169918)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST-tagged human DOT1L amino acid 1 to 472 expressed in Escherichia coli BL21 (DE3) using [3H]-SAM as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396016(CHEMBL2169918)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396016(CHEMBL2169918)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of G9a using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed