BDBM50396077 CHEMBL1229525

SMILES Cn1cc(-c2cc3cccnc3[nH]2)c2cc(ccc12)C(=O)NC(C)(C)CO

InChI Key InChIKey=XZRYCTLOGNCQDG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396077   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel

Curated by ChEMBL

LigandBDBM50396077(CHEMBL1229525)Copy SMILESCopy InChI

Affinity DataIC50:  570nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in Anti-IgG-stimulated FcgammaR-mediated leukotriene LTC4 production by fluoresce...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDB

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI